The Corporate Governance & Nominating Committee of the BioMarin Board of Directors has ultimate authority to oversee the Program and Chief Compliance Officer. The intent of the Board and Company officers is to set the tone for the ethical behavior expected of all Directors, officers, employees, and business partners.

The Chief Compliance Officer has primary responsibility for strategic program planning related to the Program including ensuring that the Program’s training, policies and procedures, communications, auditing and monitoring, and corrective action processes are developed, in place, and modified as needed. The Chief Compliance Officer reports to the Chief Legal Officer and to the BioMarin Board of Directors.

BioMarin’s Global Code of Conduct & Business Ethics and the various compliance policies, procedures, and/or processes are integrated across the organization with department specific procedures or guidance as needed. Among other things, our policies and procedures are based upon the PhRMA Code on Interactions With Healthcare Professionals. BioMarin Directors, officers, and employees are expected to comply with all of BioMarin’s global compliance policies, procedures, and processes. The total value of all gifts, promotional materials of monetary value, and incentives that may be provided to any individual medical or healthcare professional (HCP) during any calendar year shall not exceed $3,500.00. Amounts paid to HCPs for bona fide services they have provided to BioMarin and similar payments permitted under the PhRMA Code, are excluded from this cap. This annual limit shall be monitored and subject to periodic review by the Corporate Compliance department.

We’re also committed to doing business ethically and in compliance with both the letter and spirit of anti-bribery and anti-corruption (ABAC) laws. Read more in our ABAC policy.

Education is a key element of our Program. Upon hire, all employees receive Corporate Compliance training on the Code and other Corporate Business Policies. The Code is assigned to new hires and all employees for certification that they have read and understood it, and they are required to re-certify annually. Corporate Business Policies are also assigned to relevant employees for regular certification. Specialized training occurs in specific departments and across the Company for issues where compliance risks might be greater or where a need for additional training has been identified. The specialized training may include, but is not limited to, the prohibition of off-label promotion, and data privacy. In addition, Corporate Compliance personnel address compliance issues at regional and national Company meetings. The Code, Corporate Business Policies, and trainings are updated as needed for reasons including: changes in the law, new risk areas, and changes to the PhRMA Code or other regionally specific codes or laws.

BioMarin is committed to maintaining the awareness of the Program through communication to its employees. BioMarin distributes communications to employees through a variety of methods including but not limited to: all-hands meetings, and Company-wide emails. BioMarin also maintains a toll-free hotline (by phone or online) for reporting compliance concerns, as well as a process for investigating, documenting, and remediating such concerns. In the US, reporters can reach the hotline online by calling +1 (866) 513-7198. Other countries’ access numbers, as well as the ability to report online, are available at www.biomarin.ethicspoint.com. BioMarin encourages Directors, officers, and employees to promptly report suspected or actual violations of our Program and laws and regulations governing our business. Our toll-free hotline allows for anonymous reporting (except where prohibited by law) and is monitored by the Corporate Compliance department and Chief Compliance Officer.

As part of the Program, BioMarin will conduct auditing and monitoring activities designed to assess compliance with the Program’s policies, procedures, and processes, identify potential training needs, and identify policy, procedure, or process needs.

BioMarin is committed to an effective compliance Program. Enforcement action for compliance Program violations is addressed in the Code and various Human Resources policies.

The Program includes the investigation and response to identified or reported compliance issues. The response and level of investigation depends upon the reported or detected issue. The Chief Compliance Officer oversees the investigation and any resulting corrective action that is determined necessary. Corrective action may range from taking appropriate disciplinary action, modifying policies, procedures or processes, employee education, or other action designed to prevent future violations.

BioMarin is committed to compliance and strives to maintain an active and effective Program.

Based upon our good faith understanding of the California Health and Safety Code sections 119400 and 119402, BioMarin declares that, as part of its continued efforts in the area of compliance, we have developed a comprehensive Corporate Compliance Program for our commercial operations as required by the Code. To our knowledge, we are, in all material respects, in compliance with our Program.

Copies of this declaration may be obtained by calling +1 (415) 506-6700.

June 30, 2025