Who We Are

BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions.

Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions.

Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world.

About Technical Operations

BioMarin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin’s cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients.

 Senior Research Associate 2

Location: Shanbally, Cork (Onsite)

Closing Date : Monday 10th August 2026 

Summary Description 
Perform, document and develop experimental studies to troubleshoot, support process characterization and continuous process improvement activities in collaboration with cross-functional stakeholders as part of the BCoE or Site strategy, and/or in support of BioMarin’s commercial & clinical product portfolio.
Responsibilities 
Laboratory /Project work:

• Design and executes studies under guidance to support process investigations, process improvements, and other manufacturing projects in BCoE with lab scale upstream processes in a multi-product lab.
• Facilitate investigations to help understand and resolve complex manufacturing issues and assess their potential impact to product quality.
• Evaluate new methods, new technologies and implement process improvements.
• Demonstrates rapid learning of scientific techniques, principles, and protocols, consistently executing work reliably and independently.
• Effectively summarizes findings and contributes to the preparation of memoranda, technical reports, and other scientific documentation.
• Ensure personal training requirements are completed in compliance with site procedures.
• Actively work to establish and demonstrate a safety-oriented culture and to meet or exceed environmental and other regulatory requirements.
• Has a strong understanding of aseptic operations, with significant hands-on experience working in biosafety cabinets and in the preparation, operation, and monitoring of bench-scale bioreactors.
• Experience in mammalian cell culture activities, including cell thawing and cell banking, seed train expansion etc.
• Experience in bioprocessing, including bioreactor inoculation, daily monitoring, sampling and in-process analysis utilizing standard bioprocess analytical equipment.
• Understanding of perfusion bioprocess.
• Understanding of depth filtration and ultrafiltration.
• Maintains and updates SOP and BPD documentation as required, ensuring accuracy, compliance, and continuous improvement of documented processes.
• Understanding of microbial cell expansion and fermentation process execution is desirable.
• Understanding of downstream purification process is desirable.

 
General:

• Plan, execute and complete projects independently.
• Generates, reviews, and interprets data, conducts data analysis, and supports the authoring of memoranda, protocols, and technical reports, incorporating feedback and guidance as needed.
• Maintain up-to-date documentation of laboratory work carried out including documentation storage and archiving in accordance with GLP.  
• Support maintenance and calibration of lab equipment with accompanying documentation.
• Contribute to the evaluation of new equipment.
• Be a team player with excellent communication skills.
• Play an active role in maintaining and enhancing the safety of the workplace and the laboratories.
• Comply with applicable GxP regulations, SOPs, HSE, & other guidelines in the laboratory as applicable
• May be required to work periodically out of normal business hours.

Key Performance Metrics:

• Adherence to project plans & deliverables
• Adherence to applicable GxP and EHS requirements
• Technical reports executed on time and on quality
• Efficient technical exchange with Project leads

Education
Master’s degree or higher in Science or Engineering
 
Experience 

• A minimum of 3 years’ experience in the pharmaceutical industry or equivalent strong laboratory experience.
• Working knowledge of pharmaceutical regulatory requirements appropriate to level and understanding of the cGMP manufacturing process for Biologics

Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Ireland Safety Responsibility Support the organisation’s commitment to environmental protection, injury prevention, and continual improvement of EHS management systems. Actively contribute to a safe and environmentally responsible workplace by identifying hazards, reporting incidents and participating in EHS initiatives and training.
Ireland Safety Responsibility
Support the organisation’s commitment to environmental protection, injury prevention, and continual improvement of EHS management systems. Actively contribute to a safe and environmentally responsible workplace by identifying hazards, reporting incidents and participating in EHS initiatives and training.